LOL. That Hannah-Barbera style of animation always brings back a lot of memories. Mike Tyson Mysteries reminds me of Scooby-Doo, The Funky Phantom Ghost, Goober And The Ghost Chasers, Clue Club and others.
Then, it also reminds me of The Harlem Globetrotters cartoons. Later, in a company under Hannah-Barbera called Rubi & Speers, there was Rickety Rocket, Mister T., and Sports Stars with Michael Jordan, Wayne Gretzky , Bo Jackson and Dr. Ruth Westheimer. I recall that Muhammad Ali had an animated cartoon once on Saturday mornings(that one came on real early). That's what I love about Adult Swim, it is for adults(although I do miss the anime like Cowboy Bebop). I think it might work out for Mike Tyson(his one man show was very interesting as it was also funny, insightful and sad).